Common Issue Texts Comorbidities Does atomoxetine increase the risk of aggression and hostility in children with ADHD
| Does atomoxetine increase the risk of aggression and hostility in children with ADHD |
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A 13-year old boy with a diagnosis of Attention Deficit Hyperactivity Disorder (ADHD) comes to the clinic with his mother for a review. He was started on atomoxetine 6 weeks prior to this visit for hyperactive/impulsive symptoms and poor concentration. The boy was admitted to the hospital one week ago for changed behaviour, disorientation, irrelevant speech and self-harming behaviour. He was reported as very aggressive and hostile towards other children and adults. Investigation for organic causes was undertaken and no clear explanation found. He was discharged on day 3 upon improvement of symptoms. Although the diagnosis of ADHD had been some time ago, stimulant medications were not used because of the risk of abuse and drug diversion. Mother ascribes this hospitalization to a side effect of atomoxetine as he had not shown such behaviour before starting on treatment and there is no recent history of head injury, illness or change in family dynamics. She asked your opinion about increased aggression and hostility related to atomoxetine.
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